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JRCERT Update








          on humans in 1954, and by the early 1960s, health care   complications. Boosters are important to prevent infec-
          professionals switched from using the inactivated vac-  tions from new variants of the virus. To monitor safety
          cine to Sabin’s live attenuated one, which was more   and efficacy, the CDC has continued to conduct vac-
          effective, more economical, and easier to administer.   cine effectiveness research that informs new vaccine
          As a result, the Sabin vaccine soon became the world’s   development, provides new recommendations, and
          weapon against polio and has nearly eradicated the   improves policies.  These studies include prospective
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          virus worldwide. 7,8                               cohorts (frontline workers and children), household
            There are still many diseases today, including   transmission studies (health care workers and those
          influenza, chronic hepatitis B, and COVID-19, for   who live with them), and test-negative prospective
          which outcomes can be improved with vaccines. For   case–control pharmacy testing (patients and health
          example, the seasonal influenza vaccine helps pre-  care workers). 17
          vent serious complications by reducing the severity   More recently, mpox has been identified as a
          of the disease.  According to the Centers for Disease   global concern.  As of November 18, 2022, a total
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          Control (CDC), influenza-related hospitalizations   of 80 249 cases have been confirmed globally with
          in the United States have ranged from 140 000 to   29 133 cases in the United States, including 2 deaths.
          710 000 and deaths from 12 000 to 52 000 annually   Two vaccines have been approved for use in preventing
          between 2010 and 2020.  Chronic hepatitis B affects   mpox, JYNNEOS (Bavarian Nordic) and ACAM2000
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          approximately 880 000 people in the United States,   (Emergent Product Development Gaithersburg, Inc).
          causing liver disease that includes cirrhosis and can-  Their effectiveness is not yet known. 19
          cer.  COVID-19 cases, deaths, and hospitalizations in
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          the United States are trending down. According to the   Vaccine Recommendations
          CDC, 79.9% of the U.S. population has received at least   The vaccines recommended for health care work-
          1 dose of COVID-19 vaccine, 68.1% have completed the   ers by the CDC are included in Table 1. Adherence
          first series, and 35.5% of those 5 years and older have   to specific recommended timeframes for each sub-
          received the first booster. 12                     sequent vaccination dose is important. Although
                                                             medical records of vaccinations are important, blood
          Recent Developments in Immunizations               tests that show immunity also can be used to docu-
            According to the CDC, current vaccines do not use a   ment vaccinations. In addition to these recommended
          live virus, cause infection, or affect genes.  The mRNA   vaccines, vaccines are available for hepatitis A, pneu-
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          vaccines have an important role in vaccinations for   mococcal disease, shingles (herpes zoster), and human
          COVID-19. The advantages of mRNA vaccines include   papillomavirus;  these additional vaccines might be
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          quick manufacturing time and no risk of causing the   recommended for some people, including some health
          disease.  The COVID-19 pandemic accelerated the    care workers, depending on their age or other circum-
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          development of mRNA vaccines by Pfizer-BioNTech    stances.
          and Moderna, and the U.S. Food and Drug Admin-        In the United States, students and health care work-
          istration issued an emergency use authorization in early   ers are required to obtain vaccinations. The laws vary
          December 2020.  An mRNA vaccine promotes the       by state but might include assessing vaccination status
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          creation of proteins identical to those created during an   of workers, requiring vaccinations or valid exemptions,
          infection that trigger the immune system to fight when   and wearing a mask if unvaccinated for influenza.
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          an actual infection occurs.  Additional mRNA vaccines   Medical records of vaccination for students and health
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          are being developed, including an influenza vaccine. 1,3  care workers, including clinical faculty, must be kept
            The COVID-19 vaccines have been found to be      current and on file so that health care institutions and
          safe and effective.  Although breakthrough cases of   clinical sites associated with an education program
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          infection are possible as with any vaccine, they help   can confirm that requirements for patient safety and
          to decrease the severity of the illness and prevent   accreditation standards are met.  Students can obtain
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          RADIOLOGIC TECHNOLOGY, March/April 2023, Volume 94, Number 4                                    309
          Reprinted with permission from the American Society of Radiologic Technologists for educational purposes. ©2023. All rights reserved.
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